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lnterpatient heterogeneity makes it difficult to find the first suitable patient to dose
We need to maximize our asset's likelihood of success by finding the
Early identification of potential resistance mechanisms can reduce late-

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Simulations of complex cellular signaling networks to predict synthetic lethal opportunities
Novel ideas for synergistic combination therapies across modalities
Novel ideas for synergistic combination therapies across modalities
Unique benefits only delivered by Turbine
Broader clinical search space by generating unique patient representative avatars
Patient relevant testable and actionable blomarker hypotheses to guide the next stage of benchtop therapeutic research
Mechanistic link between drug and biomarkers to ensure that the therapeutic effects in preclinical models are more likely to be replicated in clinical
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Why trust us?

4
4 months from AI training to ranked hypotheses
418
218 drug – gene alteration combination tested in 301  patient derived in silico avatars
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Predicted 28 significant disease subtype associated biomarkers
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Learn more about our technology and proof points
Approach Science

How can you work with us?

INPUT

Viability Data: IC50 values for a subset of payloads tested across 10-40 cell lines, if available.

Omlcs Data: Pre- and post-treatment transcriptomics (RNA-seq), if available, for additional training and validation.

Contextual Information: Payload mechanism of action and any known resistance or sensitivity data (e.g., efflux pump involvement).

VIRTUAL LAB

in silico pharmacology screen of your payloads across a diverse panel of 1400+ virtual cell lines

In silico drug modifier KO screen of your payloads, across a diverse panel of 1400+ virtual cell lines

DELIVERY

ptOmlcs Data: Pre-and post-treatment transcriptomics (RNA-seq), if available, for additional training and validation.

pt Viability Data: IC50 values for a subset of payloads tested across 10-40 cell Iines, if available.

Causality Insights: Payload mechanism of
action and any known resistance or sensitivity data (e.g., efflux pump involvement).

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Reach out for a call
Turbine's Virtual Lab is available
for ADC Payload Selection.
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Turbine's Virtual Lab is available
for ADC Payload Selection.
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